Author

Barbara Aleksandra Potempa

University of LouisvilleORCID 0000-0002-1226-6952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jan PotempaiD· 2 shared Juhi BagaitkariD· 2 shared Andrew Fuchs· 1 shared Carlos J. Rodriguez HernandeziD· 1 shared Danuta MizgalskaiD· 1 shared Florian VeillardiD· 1 shared John D. PerpichiD· 1 shared Justyna FolkertiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Jan PotempaORCID

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2 papers

Recent·Most cited

A moonlighting serpin of Tannerella forsythia compromises the bactericidal activity of neutrophils

Savannah C Morris, Florian Veillard, Danuta Mizgalska, Mariusz Madej, Małgorzata Benedyk‐Machaczka, Justyna Folkert, Barbara Aleksandra Potempa, Andrew Fuchs, Jan Potempa, Juhi Bagaitkar

This study identifies miropin, a prokaryotic serpin from Tannerella forsythia, which suppresses neutrophil antimicrobial activity by inhibiting serine proteases and myeloperoxidase, promoting bacterial survival in vivo.

bioRxiv · Oct 9, 2026 · PreprintImmunology

Virion stripping: A new role for bacterial proteases

Carlos J. Rodriguez Hernandez, Marina Terekhova, Phylip Chen, John D. Perpich, Barbara Aleksandra Potempa, Katherine Carey, Mark E. Peeples, Mitchell H. Grayson, Jan Potempa, Maxim N. Artyomov, Richard John Lamont, Juhi Bagaitkar

This paper shows that Porphyromonas gingivalis proteases reduce viral load and modulate host interferon responses during RSV infection.

bioRxiv · May 3, 2025 · PreprintMicrobiology