Mark E. Peeples

This study shows that Caspase-11 worsens severe SARS-CoV-2 by increasing inflammation and reducing CD8 T-cell immunity, but its removal improves viral clearance and survival.

This study shows that human cardiomyocytes with trisomy 21 are more susceptible to SARS-CoV-2 infection and show an amplified immune response compared to euploid controls.

This study shows that influenza D virus efficiently replicates in human airway cells and tissues, evades innate immune responses, and may pose a zoonotic threat.

This study uses an automated behavioral system and transcriptomic analysis to identify cognitive impairments in mice with long COVID, finding similar transcriptomic changes to humans.

This paper shows that Porphyromonas gingivalis proteases reduce viral load and modulate host interferon responses during RSV infection.

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.