Kathleen A. Martin

Decay chemicals activate a pH-sensing pathway to initiate a persistent state

The paper shows that cadaverine activates trigeminal chemosensation in zebrafish, leading to a persistent behavioral state through pH sensing, independent of olfaction.

Rhomboid protease Rhbdl2 regulates macrophage recruitment and wound regeneration in zebrafish

Loss of the rhomboid protease Rhbdl2 in zebrafish larvae speeds tail fin regrowth after injury, raises macrophage accumulation and Rac2 protein, and Rac2 knockdown reverses both effects.

Vagus nerve stimulation recruits the central cholinergic system to enhance perceptual learning

This study shows that vagus nerve stimulation enhances perceptual learning in mice by activating the central cholinergic system during auditory tasks.

Integrin-deficient T cell leukemia accumulates in the central nervous system

This study shows that integrin-deficient T-cell leukemia accumulates in the CNS and proliferates faster, suggesting integrins normally restrict T-ALL growth there, and integrin blockade could enhance chemotherapy.

Neural circuitry for maternal oxytocin release induced by infant cries

The paper identifies a neural circuit in mice that links infant cries to oxytocin neuron activation, showing how auditory cues influence maternal behavior through thalamic input.

Motor cortical output for skilled forelimb movement is selectively distributed across projection neuron classes

The paper shows that different components of motor commands are distributed across two types of cortical projection neurons in mice.

Innate sensitivity and plastic mechanisms in auditory cortex for reliable maternal behavior

The paper shows that maternal behavior in mice arises from innate auditory cortex sensitivity combined with experience-dependent plasticity, enabling reliable pup retrieval.

eIF2B activator prevents neurological defects caused by a chronic Integrated Stress Response

The paper shows that a novel eIF2B activator prevents neurological defects in a mouse model of Vanishing White Matter disease by normalizing the transcriptome and proteome.

Behavioral evidence for feedback gain control by the inhibitory microcircuit of the substantia nigra

The paper tests a gain control model of the substantia nigra microcircuit by suppressing intranigral inhibition and observes behavioral effects consistent with the model.