Seung Kuk Park

The paper identifies enhancer-like elements on ecDNA in colorectal cancer that are derived from transposable elements and are functionally active in cancer cell fitness.

This study determines the structural basis for how a domesticated reverse transcriptase evolved to function in DNA repair by revealing key structural adaptations in its apoenzyme and DNA synthesis complexes.

The paper identifies mechanisms by which an RT-Cas1 fusion protein integrates RNA into DNA genomes through cDNA synthesis and site-specific integration.

The paper identifies a bacterial group II intron-like reverse transcriptase involved in DNA repair via microhomology-mediated end joining.