Author

Sara Calafate

VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0002-1276-3211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bart De StrooperiD· 2 shared Dietmar Rudolf ThaliD· 2 shared Joris de WitiD· 2 shared Joris VandenbemptiD· 2 shared Keimpe D. B. WierdaiD· 2 shared Mark W. E. J. FiersiD· 2 shared Nicola ThruppiD· 2 shared Suresh Kumar PoovathingaliD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Bart De StrooperORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 31, 2026

Multimodal profiling and intersectional genetics reveal CA1 border inhibitory neuron diversity and postnatal emergence of retrosplenial connectivity

Natalia Martínez Vizcaíno, Nicola Thrupp, Blanca Lorente-Echeverría…·Joris de Wit

The paper identifies molecular and developmental diversity in CA1 border inhibitory neurons and shows their postnatal emergence of retrosplenial connectivity.

DOI 10.64898/2026.10.29.762784

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceMolecular NeurodegenerationPeer-reviewedSep 25, 2021

Human iPSC-derived astrocytes transplanted into the mouse brain display three morphological responses to amyloid-β plaques

Pranav Preman, Julia TCW, Sara Calafate…·Amaia M. Arranz

The paper transplants human iPSC-derived astrocytes into mouse brains to study their response to amyloid-β plaques, finding morphological changes independent of APOE alleles.

71 citationstop 1%

mousehuman

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NeurosciencebioRxivPreprintMay 21, 2021

Melanin Concentrating Hormone- and sleep-dependent synaptic downscaling is impaired in Alzheimer's Disease

Sara Calafate, Gökhan Özturan, Nicola Thrupp…·Joris de Wit

This study identifies impaired MCH-system function in AD models and patients, disrupting synaptic downscaling and neuronal activity stability.

DOI 10.1101/2021.05.21.445007

mousehuman

𝕏 PostBluesky