Author

Alice E. Adriaenssens

University College LondonORCID 0000-0002-1279-4763Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:behavioral assay· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alejandro López-Cruz· 2 shared Daniel I. BrierleyiD· 2 shared Fiona Mary GribbleiD· 2 shared Frank M. ReimanniD· 2 shared Kathryn Xie· 2 shared Natalie S. Figueredo Burgos· 2 shared Stefan TrappiD· 2 shared Zachary A. KnightiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Alejandro López-Cruz

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3 papers

Recent·Most cited

An area postrema GLP-1R to NTS pathway dissociates semaglutide-induced satiation, nausea and reduced food motivation from satiety

Lauren Jones, Ella Cross, Yuqi Song, Nicholas Monaco, Phoebe Claxton, Yu Yuan, Stefan Trapp, Alice E. Adriaenssens, Daniel I. Brierley

This study identifies distinct neural circuits in the brainstem mediating semaglutide's effects on satiation, nausea, and food motivation, showing they are dissociable and involve GLP-1R and non-GLP-1R neurons.

bioRxiv · Aug 19, 2026 · PreprintNeuroscience

Opposing GIPR brainstem circuits differentially control feeding behaviour

Natalie S. Figueredo Burgos, Alejandro López-Cruz, Cecilia Skoug, Anna G. Roberts, Kathryn Xie, Iona Davies, Norio Harada, Nobuya Inagaki, Frank M. Reimann, Fiona Mary Gribble, Ben Jones, Daniel I. Brierley, Stefan Trapp, Zachary A. Knight, Alice E. Adriaenssens

The paper identifies opposing roles of GIPR neurons in the area postrema and nucleus tractus solitarius in controlling feeding behavior and satiation.

bioRxiv · Jul 7, 2026 · PreprintNeuroscience

Functional segregation of body-brain signals in the area postrema

Alejandro López-Cruz, Natalie S. Figueredo Burgos, Anna M. Hakimi, Kathryn Xie, Mo Mao, Mahekdeep Kaur, Antionette Spina, Katie Choi, Longhui Qiu, Teresa E. Lever, Fiona Mary Gribble, Frank M. Reimann, Martin Grosvenor Myers, Alice E. Adriaenssens, Zachary A. Knight

The paper identifies distinct AP neuron subtypes that respond to different macronutrients and physiological signals, revealing their roles in satiety and homeostasis beyond nausea.

bioRxiv · Jun 19, 2026 · PreprintNeuroscience