Yu Liu

Overexpression of miR-424(322)/-503 induces severe dilated cardiomyopathy by regulating the fatty acid oxidation gene expression program

This study shows that overexpression of miR-424(322)/-503 in the heart causes severe dilated cardiomyopathy by disrupting fatty acid oxidation and metabolic function.

Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

This study shows that XBP1 in myofibers regulates muscle regeneration through cell-autonomous and non-autonomous mechanisms by affecting satellite cells and non-myogenic cells.

β1 integrins regulate cellular behaviors and cardiomyocyte organization during ventricular wall formation

This study investigates the role of β1 integrins in regulating cardiomyocyte behavior and organization during ventricular wall formation in mice, finding that their deletion disrupts tissue architecture and trabeculae formation.

Chronic estrus disrupts uterine gland development and homeostasis

This study shows that chronic estrus, caused by disrupted gonadotropin-releasing hormone signaling, leads to uterine gland pathologies in female mice.

Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF induced pain

This study identifies GM-CSF's role in bone cancer pain by upregulating voltage-gated sodium channels via Jak2/Stat3 signaling in DRG neurons.