Radbod Darabi

Lipoproteins modulate the uptake and biological functionof cationic cell-penetrating peptides across the animal lineage.

This study identifies lipoprotein-mediated endocytosis as a conserved mechanism for cationic cell-penetrating peptides across animal lineages, showing it modulates their antimicrobial function.

Aberrant ciliogenesis induced by enhanced BMP signaling causes heterotopic ossification

This paper identifies BMP signaling as a driver of heterotopic ossification by promoting ciliogenesis and establishing a sensitized signaling hub that facilitates osteochondrogenic differentiation.

The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice

This study shows that POGLUT1 is essential for muscle stem cell development and maintenance in mice, with loss of function leading to muscle defects and impaired repair.

Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

This study shows that XBP1 in myofibers regulates muscle regeneration through cell-autonomous and non-autonomous mechanisms by affecting satellite cells and non-myogenic cells.