Dusan Bogunovic

Cross-source proteogenomic profiling of human microglia reveals a conserved core membrane protein and HERV signature

This study compares transcriptome and proteome profiles of three microglia sources, identifying shared surface markers and HERV expression patterns, suggesting MDMi as a practical model for functional studies.

TBK1 and IKKϵ protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism

This study shows that TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing by suppressing inflammatory apoptosis and NFκB-driven inflammation.

Broad-spectrum RNA antiviral inspired by ISG15-/- deficiency

The paper identifies a set of 10 ISGs that confer broad-spectrum antiviral resistance and demonstrates their efficacy in protecting against multiple viruses in vivo.

Multi-batch cytometry data integration for optimal immunophenotyping

The paper introduces iMUBAC, a framework for integrating multi-batch cytometry data to identify cell types and detect immunophenotype abnormalities across datasets.