Author

Samuel C. Durley

University of OxfordORCID 0000-0002-1316-2426Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Chen‐Chun PaiiD· 2 shared Stephen E. KearseyiD· 2 shared Timothy C. HumphreyiD· 2 shared Andrea KeszthelyiiD· 1 shared Antony M. CarriD· 1 shared Boon-Yu Wee· 1 shared Carol A Walker· 1 shared Charalampos RallisiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Chen‐Chun PaiORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 26, 2020

Persistent broken chromosome inheritance drives genome instability

Chen‐Chun Pai, Samuel C. Durley, Wei‐Chen Cheng…·Timothy C. Humphrey

The paper shows that inherited broken chromosomes in S. pombe undergo cycles of replication and processing, leading to chromosomal instability and rearrangements.

DOI 10.1101/2020.08.26.268565

yeastDNA methylation

𝕏 PostBluesky

Molecular BiologyJournal of Cell SciencePeer-reviewedJan 23, 2019

An essential role for dNTP homeostasis following CDK-induced replication stress

Chen‐Chun Pai, Kuo‐Feng Hsu, Samuel C. Durley…·Timothy C. Humphrey

The paper shows that disrupting dNTP homeostasis is synthetically lethal with CDK-induced replication stress in fission yeast, leading to genome instability and cell death.

22 citations

yeastexperimental assay

𝕏 PostBluesky