Author

Courtney R. Benoit

Brigham and Women's HospitalORCID 0000-0002-1334-3323Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nicholas T. SeyfriediD· 3 shared Philip L. De JageriD· 3 shared Tracy L. Young‐PearseiD· 3 shared Duc Minh DuongiD· 2 shared Garrett M. FogoiD· 2 shared Gizem TerzioğluiD· 2 shared Zachary M. AuguriD· 2 shared Aimee J. AylwardiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Nicholas T. SeyfriedORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 27, 2025

INPP5D/SHIP1 regulates endo-lysosome function and cargo-selective phagocytosis in human microglia

Gizem Terzioğlu, Emma S. Karp, Sarah E. Heuer…·Tracy L. Young‐Pearse

This study shows that INPP5D/SHIP1 regulates endo-lysosomal function and cargo-selective phagocytosis in human microglia, linking its dysfunction to Alzheimer's disease pathology.

4 citations

humanproteomics

NeurosciencebioRxivPreprintSep 20, 2025

BAG3 coordinates astrocytic proteostasis of Alzheimer's disease-linked proteins via proteasome, autophagy, and retromer complex interactions

Zachary M. Augur, Garrett M. Fogo, Courtney R. Benoit…·Tracy L. Young‐Pearse

This study identifies BAG3's role in astrocytic proteostasis in Alzheimer's disease by showing its interactions with autophagy, proteasome, and retromer components, and its impact on Aβ clearance.

2 citations

humanscRNA-seq

NeurosciencebioRxivPreprintFeb 25, 2023

Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1

Hyo Lee, Aimee J. Aylward, Richard V. Pearse…·Tracy L. Young‐Pearse

This study shows that SORL1 loss reduces APOE levels specifically in neurons and astrocytes, linking SORL1 and APOE to Alzheimer's disease risk through distinct pathways.

4 citations

humanbulk RNA-seq