Author

Yang Eric Guo

Whitehead Institute for Biomedical ResearchORCID 0000-0002-1369-7340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra Dall’AgneseiD· 1 shared Brian J. AbrahamiD· 1 shared Carrie M. Garrett-Engele· 1 shared Dongdong FuiD· 1 shared Esmée de Zwaan· 1 shared Haiting Ma· 1 shared Henry W. LongiD· 1 shared Jacob Fuglsbjerg Jeppesen· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Alessandra Dall’AgneseORCID

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1 paper

Recent·Most cited

A nuclear receptor facilitates differentiation of human PSCs into more mature hepatocytes

Haiting Ma, Esmée de Zwaan, Yang Eric Guo, Paloma Cejas, Prathapan Thiru, Martijn van de Bunt, Jacob Fuglsbjerg Jeppesen, Sudeepa Syamala, Alessandra Dall’Agnese, Brian J. Abraham, Dongdong Fu, Carrie M. Garrett-Engele, Tony Lee, Henry W. Long, Linda Gay Griffith, , Rudolf Jaenisch

This study identifies thyroid hormone receptor THRB as a key regulator of hepatocyte maturation from human PSCs, showing that T3 treatment enhances gene expression and epigenetic features of mature hepatocytes.

bioRxiv · Mar 24, 2022 · PreprintDevelopmental Biology