La’Akea Siverts

This paper introduces a new system for activating and recording thousands of neurons over a large field-of-view with pixel-level precision.

The paper integrates transcriptomic, morphological, and electrophysiological data to define neuron types in mouse visual cortex and predict their projection targets.

The paper investigates how environmental novelty affects cortical plasticity during navigation using optogenetic stimulation and calcium imaging in mice.

The paper introduces a method to monitor and control neural activity at cellular resolution in mice, discovering new cell types with unique functional properties.

This study shows that cholinergic neuron activity promotes both healthy OPC and DMG proliferation through muscarinic receptors, with specific nuclei driving growth in different brain regions.

The paper presents a synaptic physiology dataset and analysis platform to study cortical microcircuit structure and synaptic properties in mouse and human neocortex, revealing layer-dependent connectivity and subclass-specific dynamics.

The paper develops enhancer viruses and a transgenic mouse line to enable combinatorial labeling of specific neuronal subclasses in the mouse cortex and human slices.

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.