Travis A Hage

This study shows early-life stress alters chromatin modifications in the VTA, increasing stress sensitivity through changes in histone dynamics and Setd7 activity.

The paper identifies impaired SK channel function in mesolimbic dopamine neurons as a mechanism driving reward seeking adaptations in chronic neuropathic pain.

The paper presents a synaptic physiology dataset and analysis platform to study cortical microcircuit structure and synaptic properties in mouse and human neocortex, revealing layer-dependent connectivity and subclass-specific dynamics.

The paper measures synaptic inputs onto superficial excitatory neurons in mouse primary visual cortex using two-photon optogenetic stimulation and finds that layer 4 excitatory neurons and somatostatin-neurons in layer 2/3 are the most common sources of input, with strong connections distributed across cells.

The paper presents a method combining spatial transcriptomics with optogenetic mapping to resolve cell type characteristics in mouse cortex.

The paper examines sparse excitatory connectivity in adult mouse and human cortex using electrophysiology and optogenetics, finding sparse connections and synaptic dynamics across layers.

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.