Author

Aurélie Genoux

Centre National de la Recherche ScientifiqueORCID 0000-0002-1397-191XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Béatrice EyminiD· 1 shared Caroline BaretteiD· 1 shared Didier AuboeufiD· 1 shared Didier DecaudiniD· 1 shared Élodie MontaudoniD· 1 shared Fariba NématiiD· 1 shared Hélène PolvècheiD· 1 shared Nour Jamal-El-Hussein· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Béatrice EyminORCID

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1 paper

Recent·Most cited

The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer

Nour Jamal-El-Hussein, Shipra Chaudhary, Élodie Montaudon, Fariba Némati, Aurélie Genoux, Hélène Polvèche, Rania El Botty, Caroline Barette, Tao Jia, Didier Auboeuf, Didier Decaudin, Béatrice Eymin

This paper shows that the SF3B1 inhibitor pladienolide B inhibits DNA damage repair and counteracts platinum resistance in NSCLC by inducing genomic instability and altering DNA repair gene splicing.

bioRxiv · Feb 19, 2026 · PreprintCancer Biology