Author

Rania El Botty

Institut CurieORCID 0000-0002-8885-4304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Astrid LièvreiD· 1 shared Aurélie GenouxiD· 1 shared Béatrice EyminiD· 1 shared Briaux Adrien· 1 shared Caroline BaretteiD· 1 shared Cindy NeuzilletiD· 1 shared Didier AuboeufiD· 1 shared Didier DecaudiniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 19, 2026

The SF3B1 inhibitor pladienolide B massively inhibits DNA damage signaling and repair and counteracts resistance to platinum salts in Non-Small Cell Lung Cancer

Nour Jamal-El-Hussein, Shipra Chaudhary, Élodie Montaudon…·Béatrice Eymin

This paper shows that the SF3B1 inhibitor pladienolide B inhibits DNA damage repair and counteracts platinum resistance in NSCLC by inducing genomic instability and altering DNA repair gene splicing.

DOI 10.64898/2026.02.17.706284

humanbulk RNA-seq

Cancer BiologybioRxivPreprintNov 28, 2024

IKZF2-ERBB4 gene fusion leads to ERBB4 overexpression in Anal Squamous Cell Carcinoma but with no benefit for ERBB4 inhibition

Sophie Richon, Schnitzler Anne, Lamontagne Julien…·Virginie Dangles‐Marie

The paper identifies an IKZF2-ERBB4 gene fusion in Anal Squamous Cell Carcinoma leading to ERBB4 overexpression but shows that ERBB4 inhibition does not inhibit tumor growth.

DOI 10.1101/2024.11.28.625910

humanbulk RNA-seq