Christian Schulze

The paper investigates the molecular mechanisms of early and late long-term potentiation (LTP) by manipulating CaMKII activity and shows that L-LTP can occur without CaMKII activation.

The paper measures vesicular release probability at individual synapses and finds it determines synaptic strength rather than vesicle number or content.

This study shows that hyperpolarization of microglia membrane potential is essential for chemotaxis, while depolarization inhibits it.

The paper shows that endoplasmic reticulum (ER) visits active dendritic spines to prevent excessive synaptic potentiation.

The paper introduces SynTagMA, a tool to mark active synapses in a 2-second window, and provides software for analyzing large datasets of synaptic activity.

The paper investigates the relationship between diffusional coupling in dendritic spines and long-term potentiation (LTP), finding that weakly isolated spines show significant LTP while highly isolated spines do not.

The paper develops ultrafast glutamate sensors iGluu and iGluf to study high-frequency synaptic transmission, revealing presynaptic frequency-dependent filtering of spike trains.