Nordine Helassa

The paper identifies a plasma RNA signature linked to MAPK14-related inflammatory signaling as a potential marker for postoperative atrial fibrillation susceptibility.

The paper uses IVIS Lysotracker imaging and RT-qPCR to assess lysosomal abundance and autophagy-related gene expression in young and aged mouse hearts, finding preserved acidic-vesicle pool and stable gene expression.

The paper measures vesicular release probability at individual synapses and finds it determines synaptic strength rather than vesicle number or content.

The paper uses iGluu imaging to analyze glutamate clearance at single synapses in Huntington's disease mice, finding impaired uptake and release in affected synapses.

The paper develops ultrafast glutamate sensors iGluu and iGluf to study high-frequency synaptic transmission, revealing presynaptic frequency-dependent filtering of spike trains.