Single kinetochores execute an ordered series of molecular events as the Spindle Assembly Checkpoint is silenced
Catriona C. Conway, Tsvetelina E. Germanova, Sara Toral-Pérez, Catherine Coates, Jonathon Pines, Nigel John Burroughs, Andrew D. McAinsh
The paper maps the ordered molecular events of SAC silencing at single kinetochores using MAD2 levels, revealing sequential unbinding, structural reorganization, and stabilization processes.
Cell Reports · Jun 1, 2026Peer-reviewedCell Biology