Author

Valentin Guyard

Centre National de la Recherche ScientifiqueORCID 0000-0002-1453-6151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Abdou Rachid ThiamiD· 1 shared Bodan HuiD· 1 shared Cécile SauvanetiD· 1 shared Cristian Rocha‐RoaiD· 1 shared Cyrille Y. BottéiD· 1 shared Daniel ÁlvareziD· 1 shared David C. TaresteiD· 1 shared Dazhi LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Abdou Rachid ThiamORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular insights into bulk lipid transport from structural studies of the bridge-like protein VPS13A complexed with the scramblase XKR1

Bodan Hu, Daniel Álvarez, Cristian Rocha‐Roa, Valentin Guyard, Dazhi Li, Xinbo Wang, Pietro V. De Camilli, Stefano Vanni, Karin M. Reinisch

The paper uses cryo-EM to study the VPS13A-XKR1 complex, revealing how it facilitates lipid transfer between membranes and how this process is enhanced by membrane properties.

bioRxiv · Jan 8, 2026 · PreprintCell Biology

ORP5 controls the partitioning of phosphatidic acid between triacylglycerol and cardiolipin synthesis at mitochondria-ER-lipid droplet contact sites

Vera Filipa Monteiro-Cardoso, Valentin Guyard, Jennica Träger, Cécile Sauvanet, Helin Elhan, Mehdi Zouiouich, Naïma El Khallouki, Yoshiki Yamaryo‐Botté, David C. Tareste, Cyrille Y. Botté, Abdou Rachid Thiam, Francesca Giordano

This study identifies ORP5 as a key regulator of phosphatidic acid partitioning between triacylglycerol and cardiolipin synthesis at MAM-LD junctions, showing its role in balancing lipid metabolism and mitochondrial health.

bioRxiv · Nov 6, 2025 · PreprintCell Biology