Author

Joseph C. Glykys

University of IowaORCID 0000-0002-1499-9172Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Pratyush S. SuryavanshiiD· 2 shared Alexander G. BassukiD· 1 shared Angela Wong· 1 shared Budhaditya BasuiD· 1 shared Daniel R. ThedensiD· 1 shared David Keffala-Gerhard· 1 shared Elizabeth A. NewelliD· 1 shared Eric B. TayloriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Pratyush S. SuryavanshiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lysine Crotonylation Acts as an Epigenetic Switch for Glutamate Neurotransmission and Spatial Memory

Utsav Mukherjee, Budhaditya Basu, Pratyush S. Suryavanshi, Stacy E. Beyer, Saaman Ghodsi, Nathan Robillard, Yann S. Vanrobaeys, Eric B. Taylor, Joseph Glykys, Ted G. Abel, Snehajyoti Chatterjee

This study identifies lysine crotonylation (Kcr) as an epigenetic regulator of long-term memory and glutamatergic neurotransmission, showing its role in gene expression and synaptic function.

Proceedings of the National Academy of Sciences · Oct 28, 2026Peer-reviewedNeuroscience

Brief and diverse excitotoxic insults cause an increase in neuronal nuclear membrane permeability in the neonatal brain

Pratyush S. Suryavanshi, Rachel Langton, K. Fairhead, Joseph C. Glykys

The paper shows excitotoxic insults increase neuronal nuclear membrane permeability in the neonatal brain, as indicated by nuclear translocation of GCaMP6s and increased nuclear pore size.

Journal of Neuroscience · Aug 30, 2024Peer-reviewedNeuroscience

Neuroprotective Effects of Naltrexone in a Mouse Model of Post-Traumatic Epilepsy

Saul Rodriguez, Shaunik Sharma, Grant Tiarks, Zeru J. Peterson, Kyle Jackson, Daniel R. Thedens, Angela Wong, David Keffala-Gerhard, Vinit B. Mahajan, Polly J. Ferguson, Elizabeth A. Newell, Joseph C. Glykys, Thomas Nickl‐Jockschat, Alexander G. Bassuk

This study shows that naltrexone prevents neuroinflammation and epileptogenesis in a mouse model of post-traumatic epilepsy.

bioRxiv · Oct 4, 2023 · PreprintNeuroscience

Unique actions of GABA arising from cytoplasmic chloride microdomains

Negah Rahmati, Kieran P. Normoyle, Joseph C. Glykys, Volodymyr I. Dzhala, Kyle P. Lillis, Kristopher Thomas Kahle, Rehan Raiyyani, Theju Jacob, Kevin J. Staley

The paper measures chloride ion concentrations in neurons to show the existence of stable cytoplasmic chloride microdomains that affect GABAergic signaling.

Journal of Neuroscience · Apr 26, 2021Peer-reviewedNeuroscience