Yaxi Wang

This study identifies adhesin proteins in Nanosynbacteria that recognize specific host cell wall polysaccharides for recognition and attachment.

The paper identifies an Esx secretion system in Actinomycetota that defends against parasitic Patescibacteria by sensing epibionts and triggering a transcriptional response.

The paper designs high-affinity miniprotein binders targeting Flpp3, a virulence factor of Francisella tularensis, using physics-based and deep-learning methods, achieving sub-nanomolar affinities.

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

This study uses deep learning to predict protein-protein interactions in bacterial pathogens, identifying new complexes involving essential genes and virulence factors, with half of tested predictions validated.

This study identifies umbrella toxin particles produced by Streptomyces that inhibit the growth of competing bacterial species, distinct from small molecule antibiotics.