Michael W Bauer

The paper identifies sepsis subtypes in blood and liver and shows that CXCR2 blockade improves survival only in specific subtypes, highlighting the need for precision therapy.

This paper identifies transient GSK3β activation as a mechanism promoting disease tolerance to sepsis through hypometabolism, without affecting pathogen burden.

This study identifies adipocyte lipolysis as a critical metabolic process that prevents sepsis in mice by supporting energy metabolism and thermoregulation through insulin signaling, without affecting bacterial burden.

This study identifies LILRA5 as an activating receptor on phagocytes that stimulates ROS production and shows its dynamic regulation in response to infection and inflammation.

The paper demonstrates that dye-functionalized lipid nanocarriers can deliver a PI3Kγ inhibitor to hepatocytes, restoring liver function in sepsis without affecting immune responses.