Sylvaine You

This study shows that Coxsackievirus B3 evades CD8+ T-cell immunity by downregulating HLA Class I and viral peptide presentation, while inducing robust CD4+ T-cell responses and memory formation.

The paper shows that reducing MHC class I epitope trimming in NOD mice delays diabetes by altering T cell responses and epitope presentation.

This study shows RIPK1 promotes beta-cell death in autoimmune diabetes by affecting gene expression and kinase signaling, suggesting it as a therapeutic target.