Author

Holly A. Leddy

Duke UniversityORCID 0000-0002-1604-2876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alireza SavadipouriD· 1 shared Amy L. McNultyiD· 1 shared Fang LiuiD· 1 shared Farshid GuilakiD· 1 shared Robert J. NimsiD· 1 shared Whasil LeeiD· 1 shared Wolfgang LiedtkeiD· 1 shared Yong CheniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Alireza SavadipourORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMay 23, 2020

Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feedforwardmechanism

Whasil Lee, Robert J. Nims, Alireza Savadipour…·Wolfgang Liedtke

This study identifies a feedforward mechanism in osteoarthritis where IL-1-induced Piezo1 upregulation enhances mechanotransduction and contributes to cartilage damage.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky