Author

Amy L. McNulty

Duke UniversityORCID 0000-0003-0556-0106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alireza SavadipouriD· 2 shared Farshid GuilakiD· 2 shared Robert J. NimsiD· 2 shared Wolfgang LiedtkeiD· 2 shared Alison K. RossiD· 1 shared Bo ZhangiD· 1 shared Christopher J. O’ConoriD· 1 shared Fang LiuiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Alireza SavadipourORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Synthetic BiologyScience AdvancesPeer-reviewedJan 27, 2021

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani Ho…·Farshid Guilak

This paper develops a synthetic mechanogenetic gene circuit in engineered tissues that produces a therapeutic drug in response to mechanical loading.

85 citationstop 1%

experimental assaydrug response / drug discovery

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 23, 2020

Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feedforwardmechanism

Whasil Lee, Robert J. Nims, Alireza Savadipour…·Wolfgang Liedtke

This study identifies a feedforward mechanism in osteoarthritis where IL-1-induced Piezo1 upregulation enhances mechanotransduction and contributes to cartilage damage.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky