Eddy Albarran

This study shows how reinforcement learning modifies specific dendritic activity through synaptic plasticity, leading to the formation of task-relevant synaptic ensembles.

This study shows that striatal ensembles become more efficient over learning by refining activation patterns in dSPNs and iSPNs in head-fixed mice.

The paper generates and characterizes knock-in mouse lines for precise genetic targeting of striatal and dopaminergic neurons, confirming their utility for studying neural circuits and disorders.

The paper introduces a genetically encoded fluorescent sensor, GRABeCB2.0, to measure endocannabinoid dynamics with high spatiotemporal resolution in vitro and in vivo, revealing new insights into eCB signaling in neurons and brain regions.

The paper identifies synucleins as essential for vesicular exocytosis of endocannabinoids, linking their role in Parkinson's Disease to synaptic plasticity.

This study shows that increasing dendritic spine stability in motor cortex enhances motor learning in mice by improving spine survival and formation during skill acquisition.

The paper identifies a conserved cell type set in cerebellar nuclei across species and shows how it was duplicated to form new regions, with a shift in dominance in humans.