Author

Ganapathy Sriram

Koch Institute for Integrative Cancer Research At MITORCID 0000-0002-1651-3607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael B. YaffeiD· 2 shared Yi Wen KongiD· 2 shared Alexis R. BarriD· 1 shared Annabelle Sanders· 1 shared Benjamin W. Lyon· 1 shared Bert van de KooijiD· 1 shared Brian A. JoughiniD· 1 shared Brian J.P. HuntlyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Michael B. YaffeORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 20, 2026

Live immunogenic melanoma cells generated by etoposide treatment upregulate B2M and lose tumor-forming potential

Benjamin W. Lyon, Emma Russo, Cheyenne Colbert…·Ganapathy Sriram

This study shows that etoposide-treated B16-Ova melanoma cells upregulate B2M and lose tumor-forming potential while remaining viable and stimulating T-cell activation.

DOI 10.64898/2026.10.18.759921

mouseproteomics

BiochemistrybioRxivPreprintJun 10, 2025

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions

Nuo Cheng, Luis R. Millán-Barea, Marc Creixell…·Michael B. Yaffe

The paper identifies molecular determinants for phosphotyrosine recognition in tyrosine kinases and shows their roles in tumor promotion and suppression.

1 citation

mouseproteomics