Yi Wen Kong

Live immunogenic melanoma cells generated by etoposide treatment upregulate B2M and lose tumor-forming potential

This study shows that etoposide-treated B16-Ova melanoma cells upregulate B2M and lose tumor-forming potential while remaining viable and stimulating T-cell activation.

MAPKAP Kinase-2 signaling enhances the resolution of colonic inflammation through specialized pro-resolving mediators

This study shows MK2 promotes resolution of colonic inflammation by enabling the switch to specialized pro-resolving mediators, improving inflammation outcomes and tissue repair.

MAPKAP Kinase 2 Orchestrates Memory T Cell Inflation in Cytomegalovirus Infection

This study shows that MK2 regulates CD8 T cell inflation during CMV infection by affecting their expansion and differentiation.

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions

The paper identifies molecular determinants for phosphotyrosine recognition in tyrosine kinases and shows their roles in tumor promotion and suppression.

Transite: A computational motif-based analysis platform that identifies RNA-binding proteins modulating changes in gene expression

Transite identifies RNA-binding proteins modulating gene expression changes by analyzing RNA stability and degradation, validated with hnRNPC in chemotherapeutic resistance.