Author

Nuo Cheng

University of CambridgeORCID 0000-0002-2614-8682Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Nuo Cheng1 paper · Northeast Normal University

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Pau CreixelliD· 2 shared Alexis R. BarriD· 1 shared Bert van de KooijiD· 1 shared Brian A. JoughiniD· 1 shared Brian J.P. HuntlyiD· 1 shared Cécile K. LopeziD· 1 shared Chengcheng ShiiD· 1 shared Chris BakaliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Pau CreixellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologyScience SignalingPeer-reviewedJan 20, 2026

Pervanadate-induced oxidation relieves autoinhibition of SRC protein tyrosine kinase

Katie E. Mulholland, Maxime Bourguet, Nuo Cheng…·Hayley J. Sharpe

This paper shows that pervanadate induces oxidation, which activates SRC kinases by disrupting autoinhibition and altering SH2 domain phosphopeptide binding, revealing a redox-dependent mechanism for SRC activation.

8 citationstop 1%

experimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 10, 2025

Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions

Nuo Cheng, Luis R. Millán-Barea, Marc Creixell…·Michael B. Yaffe

The paper identifies molecular determinants for phosphotyrosine recognition in tyrosine kinases and shows their roles in tumor promotion and suppression.

1 citation

mouseproteomics

𝕏 PostBluesky

GenomicsbioRxivPreprintDec 12, 2021

Protective effect of peroxisome proliferator-activated receptor- in regulating the early inflammation response to extended hepatectomy from a comparative transcriptomic analysis

Chengcheng Shi, Yang Bai, Xin Yan…·Jihua Shi

The paper identifies PPAR as a potential therapeutic target for small-for-size syndrome by analyzing transcriptomic changes after extended hepatectomy in rats.

DOI 10.1101/2021.12.12.472295

ratbulk RNA-seq

𝕏 PostBluesky