Author

Mohsen Hosseini

University Health NetworkORCID 0000-0002-1686-8512Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Stephanie Zhi-Juan XieiD· 2 shared Steven M. ChaniD· 2 shared Aaron David SchimmeriD· 1 shared Abdula MaheriD· 1 shared Alex C.H. LiuiD· 1 shared Alyx E. Gray· 1 shared Andrea ArrudaiD· 1 shared Angelica VaresiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Stephanie Zhi-Juan XieORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 12, 2026

CD59 organizes the plasma membrane to sustain oncogenic Ras-MAPK signaling and is a targetable vulnerability in acute myeloid leukemia

Abdula Maher, Dhanoop Manikoth Ayyathan, Séverine Cathelin…·Steven M. Chan

This study identifies CD59 as a critical regulator of Ras-MAPK signaling in AML, showing its depletion impairs leukemic growth and identifies rILYd4 as a potential therapeutic target.

DOI 10.64898/2026.08.11.744285

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 2, 2026

Aberrant oxidative metabolism selects for TET2-deficient hematopoietic stem and progenitor cells

Katia E. Niño, Vera Ademà, Alyx E. Gray…·Eric Martin Pietras

This study shows that aberrant oxidative metabolism drives the selection of TET2-deficient hematopoietic stem and progenitor cells in clonal hematopoiesis, with the pentose phosphate pathway playing a compensatory role.

DOI 10.64898/2026.02.28.707294

mousehuman

𝕏 PostBluesky