Author

Crismita Dmello

Northwestern UniversityORCID 0000-0002-1688-9663Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Adam M. SonabendiD· 3 shared Li Chen· 3 shared Catalina Lee-ChangiD· 2 shared Dieter Henrik HeilandiD· 2 shared Joseph T. DuffyiD· 2 shared Karl John HabashyiD· 2 shared Victor Andrés ArrietaiD· 2 shared A. Karim AhmediD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

Adam M. SonabendORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJun 25, 2026

MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.

Kwang‐Soo Kim, Junyi Zhang, Victor Andrés Arrieta…·Adam M. Sonabend

This study identifies the MAPK/ERK pathway as a key regulator of glioma susceptibility to immune checkpoint blockade, showing it modulates interferon responses, T cell recruitment, and tumor-microglia interactions.

8 citationstop 1%

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologyNeoplasiaPeer-reviewedJan 6, 2026

THOC1 complexes with SIN3A to regulate R-loops and promote glioblastoma progression

Shreya Budhiraja, Umme H Faisal, Shivani Baisiwala…·A. Karim Ahmed

This study identifies THOC1 as a driver of glioblastoma progression by interacting with SIN3A to regulate R-loops and telomere stability.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 9, 2025

Targeting CHEK2-YBX1&YBX3 regulatory hub to potentiate immune checkpoint blockade response in gliomas

Heba A. Ali, Ningjia Zhou, Li Chen…·Crismita Dmello

This study identifies the CHK2-YBX1&YBX3 hub as an immunosuppressive mechanism in gliomas and shows that targeting it with SU056 enhances immune checkpoint blockade efficacy.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky