Sophie M. Travis

This study identifies how XMAP215 interacts with γ-TuRC to promote microtubule nucleation through specific TOG domains and reveals structural insights into their cooperative function.

This paper identifies two conformations of the γ-tubulin ring complex (γ-TuRC) using cryo-EM and proposes a model for how conformational changes facilitate microtubule nucleation.

The paper presents an integrated model of the vertebrate augmin complex using cryo-EM, structural prediction, and electron microscopy, revealing its structure, conservation, and microtubule binding site.