Philip D. Jeffrey

Structural insights into xyloglucan recognition by an ABC transporter from a Gram-positive, thermophilic bacterium

The paper identifies an ABC transporter for xyloglucan uptake in Anaerocellum bescii and solves its substrate-binding protein structure, revealing a unique mode of xyloglucan recognition.

Mechanism of how the universal module XMAP215 γ-TuRC nucleates microtubules

This study identifies how XMAP215 interacts with γ-TuRC to promote microtubule nucleation through specific TOG domains and reveals structural insights into their cooperative function.

Engineering auxin degradation into root-associated bacteria promotes plant growth

The paper engineers auxin-degrading bacteria to alleviate root growth inhibition and improve plant growth.

Functional and structural characterization of AtAbf43C: An exo-1,5-α-L-arabinofuranosidase from Acetivibrio thermocellus DSM1313

This paper characterizes the function and structure of AtAbf43C, an exo-1,5-α-L-arabinofuranosidase from A. thermocellus, showing it acts on arabino-oligosaccharides with a specific binding pocket and catalytic triad.

Conformational states of the microtubule nucleator, the γ-tubulin ring complex

This paper identifies two conformations of the γ-tubulin ring complex (γ-TuRC) using cryo-EM and proposes a model for how conformational changes facilitate microtubule nucleation.

The Structural Basis of Rubisco Phase Separation in the Pyrenoid

This study identifies the structural basis of Rubisco phase separation in the pyrenoid by analyzing interactions between Rubisco and its linker protein EPYC1 in Chlamydomonas reinhardtii.