Author

Matthew C. Arvin

Northwestern UniversityORCID 0000-0002-1744-2142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

David L. WokosiniD· 2 shared Luke D. LavisiD· 2 shared Ryan M. DrenaniD· 2 shared Sambashiva BanalaiD· 2 shared Xiao-Tao Jin· 2 shared Abigail Turner· 1 shared Amelia K. LinnemanniD· 1 shared Anis ContractoriD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

David L. WokosinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IFN-α Induces Heterogenous ROS Production in Human β-Cells

Leslie E. Wagner, Olha Melnyk, Abigail Turner, Bryce E. Duffett, Charanya Muralidharan, Michelle M. Martinez Irizarry, Matthew C. Arvin, Kara S. Orr, Elisabetta Manduchi, Klaus H. Kaestner, Joseph T. Brozinick, Amelia K. Linnemann

This study shows IFN-α induces heterogeneous ROS production in human β-cells, with healthier donors having more ROS-accumulating cells, and identifies enriched immune-related genes in ROS-producing cells.

bioRxiv · Feb 19, 2025 · PreprintCell Biology

Nicotinic cholinergic receptors in VTA glutamate neurons modulate excitatory transmission

Yijin Yan, Can Peng, Matthew C. Arvin, Xiao-Tao Jin, Veronica J. Kim, Matthew D. Ramsey, Yong Wang, Sambashiva Banala, David L. Wokosin, J. Michael McIntosh, Luke D. Lavis, Ryan M. Drenan

This study shows that VTA glutamate neurons express nicotinic acetylcholine receptors and are modulated by cholinergic input, affecting excitatory transmission.

Cell Reports · May 1, 2018Peer-reviewedNeuroscience

Development of photoactivatable drugs enables nicotinic optopharmacology

Sambashiva Banala, Matthew C. Arvin, Nicolas M. Bannon, Xiao-Tao Jin, Yong Wang, Guiqing Zhao, John J. Marshall, Kyle R. Gee, David L. Wokosin, Anis Contractor, Henry A. Lester, Yevgenia Kozorovitskiy, Ryan M. Drenan, Luke D. Lavis

This paper develops a method to create photoactivatable nicotine for optopharmacology studies of nicotinic acetylcholine receptors.

bioRxiv · Feb 5, 2018 · PreprintNeuroscience