Author

Katie H. Barker

University of CambridgeORCID 0000-0002-8601-4416Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

David Colin BulmeriD· 4 shared Ewan St. John SmithiD· 3 shared Fraser WelshiD· 2 shared James P. HighamiD· 2 shared Toni S. Taylor· 2 shared Catherine H. WilsoniD· 1 shared Charity N. Bhebhe· 1 shared Charles A. MeiniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersNeuroscience

David Colin BulmerORCID

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4 papers

Recent·Most cited

NeuroscienceJournal of NeurochemistryPeer-reviewedAug 1, 2025

IL-17 sensitises sensory neurons and colonic afferents to noxious stimuli in a PI3K dependent manner

Luke W Paine, James P. Higham, Katie H. Barker…·David Colin Bulmer

The paper identifies IL-17's role in enhancing pain sensitivity in the gut via PI3K-dependent mechanisms in ulcerative colitis.

4 citations

mousebulk RNA-seq

NeurosciencePainPeer-reviewedJan 29, 2024

Transcriptomic profiling reveals a pro-nociceptive role for Angiotensin II in inflammatory bowel disease

James P. Higham, Charity N. Bhebhe, Rohit A Gupta…·David Colin Bulmer

This study identifies Angiotensin II as a pro-nociceptive mediator in IBD by showing increased Agt expression and AT1 receptor activation in colonic neurons.

18 citationstop 4%

humanbulk RNA-seq

NeuroscienceThe Journal of PhysiologyPeer-reviewedJul 1, 2022

Sensitisation of colonic nociceptors by TNFα is dependent on TNFR1 expression and p38 MAPK activity

Katie H. Barker, James P. Higham, Luke A. Pattison…·David Colin Bulmer

This study shows TNFα sensitizes colonic nociceptors via TNFR1 and p38 MAPK, enhancing responses to capsaicin and noxious distension.

23 citations

mouseelectronic health records

NeuroscienceMolecular PainPeer-reviewedJan 1, 2020

Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves

James R.F. Hockley, Katie H. Barker, Toni S. Taylor…·Ewan St. John Smith

This study investigates acid and inflammatory sensitivity of colonic afferent nerves in naked mole-rats compared to mice, showing differential responses to acid and bradykinin.

9 citations

experimental assay