Cell BiologybioRxivPreprint
Delivery of caspase inhibitors through GSDMD pores to inhibit pyroptosis
Katarzyna M. Groborz, Melissa E. Truong, Irma B. Stowe…·Vishva M. Dixit
This study develops covalent caspase inhibitors that block pyroptosis and IL-1β secretion through GSDMD pores, showing therapeutic potential for inflammatory diseases.
3 citations