Cancer BiologyJournal of Medicinal ChemistryPeer-reviewed
Engineering cathepsin S selective chemical probes and antibody-drug conjugates through substrate profiling with unnatural amino acids
Maria Łęcka, Oliwia Gorzeń, Natalia Ćwilichowska-Puślecka…·Marcin Poręba
The paper develops selective chemical probes and antibody-drug conjugates for cathepsin S by profiling substrate specificity with unnatural amino acids and validates their efficacy in cancer models.
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