Author

Vishva M. Dixit

GenentechORCID 0000-0001-6983-0326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kim NewtoniD· 3 shared Joshua D. WebsteriD· 2 shared Nobuhiko KayagakiiD· 2 shared Rohit RejaiD· 2 shared Bence DánieliD· 1 shared Bettina L. Lee· 1 shared Cristhian CadenaiD· 1 shared Cynthia CheniD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

Kim NewtonORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 23, 2025

IRF2 degradation tunes the innate immune response

Cristhian Cadena, Rohit Reja, Emma Bolech…·Vishva M. Dixit

The paper shows IRF2 degradation by IRF1 during immune responses enhances ISG transcription, revealing a regulatory circuit between IRF1 and IRF2 in innate immunity.

DOI 10.1101/2025.09.23.678148

mousehuman

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Cell BiologybioRxivPreprintFeb 11, 2025

Delivery of caspase inhibitors through GSDMD pores to inhibit pyroptosis

Katarzyna M. Groborz, Melissa E. Truong, Irma B. Stowe…·Vishva M. Dixit

This study develops covalent caspase inhibitors that block pyroptosis and IL-1β secretion through GSDMD pores, showing therapeutic potential for inflammatory diseases.

3 citations

mouseproteomics

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Molecular BiologyPLoS ONEPeer-reviewedApr 5, 2019

The Gag Protein PEG10 Binds to RNA and Regulates Trophoblast Stem Cell Lineage Specification.

Mona Abed, Erik Verschueren, Hanna G. Budayeva…·Vishva M. Dixit

This study shows that PEG10 binds RNA and regulates trophoblast stem cell differentiation into placental lineages by stabilizing key RNAs like Hbegf.

81 citations

mousebulk RNA-seq

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