Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth
Collin Dube, Y. Zhang, Shekhar Saha, Tyler C J Deutsch, Matthew Yorek, Michelle Lai, Myron Keith Gibert, Miguel Escalante, Kadie Hudson, Doris Wong, Pawel Marcinkiewicz, Ulaş Yener, Yunan Sun, Esther Xu, Aditya Sorot, , Roger Abounader
This study shows that microenvironment T-type calcium channels promote glioblastoma growth by regulating neuronal and glial processes, and that blocking these channels with mibefradil enhances the effectiveness of standard therapies.
Neuro-Oncology · May 28, 2026Peer-reviewedCancer Biology