Yasuhiro Arimura

Native yeast kinetochore structures identify an essential inner kinetochore interaction

The paper identifies an essential Ndc10 trimerization interaction in yeast kinetochores that stabilizes centromeric DNA and facilitates kinetochore assembly.

IMPACTS OF DNA METHYLATION ON H2A.Z DEPOSITION AND NUCLEOSOME STABILITY

This study investigates how DNA methylation affects H2A.Z nucleosome stability and deposition, revealing SRCAP-dependent and -independent mechanisms.

MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

The paper introduces MagIC-cryo-EM, a technique that enables structural analysis of scarce macromolecules in heterogeneous samples with lower concentration requirements, and applies it to study H1.8-associated nucleosomes.

Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast

This study reveals the architecture and flexibility of native kinetochores using structural analyses of purified kinetochores from thermophilic yeast.