Author

Angelica Andrade Latino

Fred Hutch Cancer CenterORCID 0009-0009-7906-3349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Changkun HuiD· 2 shared Sue BigginsiD· 2 shared Andrew B. StergachisiD· 1 shared Andrew R. PopchockiD· 1 shared Charles L. AsburyiD· 1 shared Mengqiu JiangiD· 1 shared Sabrine HédouiniD· 1 shared Yasuhiro ArimuraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Changkun HuORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 5, 2026

Native yeast kinetochore structures identify an essential inner kinetochore interaction

Mengqiu Jiang, Changkun Hu, Sabrine Hédouin…·Sue Biggins

The paper identifies an essential Ndc10 trimerization interaction in yeast kinetochores that stabilizes centromeric DNA and facilitates kinetochore assembly.

DOI 10.1038/s41467-026-76163-6

yeastcryo-EM

𝕏 PostBluesky

BiophysicsNucleic Acids ResearchPeer-reviewedOct 14, 2025

Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres

Changkun Hu, Andrew R. Popchock, Angelica Andrade Latino…·Sue Biggins

This study directly observes the sequential and interdependent assembly of kinetochores on individual centromeres in budding yeast, revealing regulatory dependencies and a rate-limiting step in the process.

6 citations

yeastexperimental assay

𝕏 PostBluesky