Changkun Hu

The paper identifies an essential Ndc10 trimerization interaction in yeast kinetochores that stabilizes centromeric DNA and facilitates kinetochore assembly.

This study identifies an interdependent Cbf1-CCAN interaction that stabilizes the budding yeast kinetochore by coupling transcriptional roadblocking to inner kinetochore assembly.

This study shows that Cnn1 stabilizes kinetochore-microtubule attachments by enabling Stu2-dependent reinforcement, as demonstrated through in vitro assays and genetic experiments.

This study directly observes the sequential and interdependent assembly of kinetochores on individual centromeres in budding yeast, revealing regulatory dependencies and a rate-limiting step in the process.