Rui Yan

In situ molecular architecture of the mammalian sperm nuclear vacuole

The paper identifies components of mammalian sperm nuclear vacuoles using cryo-ET and AlphaFold docking, revealing proteasomes, PA200, and ferritin, and their structural roles.

Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography

The paper develops methods to analyze chromatin condensates using cryo-electron tomography and deep learning, revealing nucleosome structures and interactions in both reconstituted and native systems.

Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2

This paper reports the structure of Arabidopsis RDR2 and shows how it initiates transcription from RNA templates displaced from RNA-DNA hybrids.

VP-Detector: A 3D convolutional neural network for automated macromolecule localization and classification in cryo-electron tomograms

VP-Detector uses a 3D convolutional neural network to automatically localize and classify macromolecules in cryo-electron tomograms, achieving competitive performance with efficient processing.