Antonio Abbate

This paper demonstrates that targeting CD160+ cells with a monoclonal antibody prevents autoimmune-induced myocarditis by depleting NK cells and other cytotoxic T cells, inhibiting multiple inflammatory pathways.

This study shows that blocking IL-18 with IL-18BP improves cardiac function in mice on a Western diet, independent of weight gain and glucose tolerance.

This study investigates unconventional IL-1β signaling via PI3Kγ in cardiomyocytes, showing kinase-independent mechanisms link IL-1β to cardiac dysfunction and potential heart failure treatment insights.

This paper develops orally deliverable milk-derived nanovesicles loaded with Cx43 peptides to treat cardiac ischemia-reperfusion injury, showing >60% reduction in infarct size in mice.