Author
Brigham and Women's HospitalORCID 0000-0002-1957-9070Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Antonio P. A. Ferreira, Shumei Wang, Larysa Poluben…·Jon Christopher Aster
The paper identifies CCL19⁺ fibroblasts as a proliferative niche in chronic lymphocytic leukemia by analyzing single-cell RNA sequencing data and characterizing interactions within lymph nodes.
Ruili Cao, Oren Gozlan, Alina Airich…·Stephen C. Blacklow
This study identifies the structural requirements of MIB1 for ubiquitin transfer in Notch signaling, showing that RING3 is essential for catalytic activity and dimerization.
Julia M. Rogers, Claudia A. Mimoso, Benjamin J. E. Martin…·Stephen C. Blacklow
This study shows Notch1 activates transcription by releasing paused RNA Pol II without requiring chromatin accessibility changes.
Alexandre P. J. Martin, Gary Andrew Bradshaw, Robyn J. Eisert…·Stephen C. Blacklow
This study maps the spatiotemporal dynamics of Notch2 signaling from membrane to nucleus after ligand activation, identifying key molecular events in signal transmission.
Julia M. Rogers, Bingqian Guo, Emily D. Egan…·Stephen C. Blacklow
The paper investigates the differential requirements for MAML1 in Notch-dependent transcription at HES4 and DTX1, showing distinct functional roles of MAML1 regions and interactions with p300.