Author

Patricia A. Thistlethwaite

University of California San DiegoORCID 0000-0002-1986-7304Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aleksandra BabichevaiD· 1 shared Amin Izadi· 1 shared Ayako MakinoiD· 1 shared Brandon Biagas· 1 shared Celia R. Espinoza· 1 shared Christina M. PabelickiD· 1 shared Cole Paquin· 1 shared Courtney TindleiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Aleksandra BabichevaORCID

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2 papers

Recent·Most cited

An Endocytic Checkpoint Controls Macrophage PD-1 Function and Immunotherapy Fate

Madhubanti Mullick, Ella McLaren, Suchismita Roy, Brandon Biagas, Mahitha Shree Anandachar, Vanessa Castillo, Samuel Williams, Celia R. Espinoza, Courtney Tindle, Gajanan Dattatray Katkar, Patricia A. Thistlethwaite, Saptarshi Sinha, Pradipta Ghosh

This paper identifies GIV as a macrophage-intrinsic factor that controls PD1 endocytosis, determining durable response versus hyperprogressive disease to PD1 blockade.

bioRxiv · Apr 17, 2026 · PreprintCancer Biology

Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells

Aleksandra Babicheva, Ibrahim Shehata Elmadbouh, Shanshan Song, Michael A Thompson, Ryan Powers, Pritesh Jain, Amin Izadi, Jiyuan Chen, Lauren Yung, Sophia Parmisano, Cole Paquin, Wei‐Ting Wang, Yuqin Chen, Ting Wang, Mona Alotaibi, , Jason X.‐J. Yuan

This study shows that TGF-β1-induced endothelial-to-mesenchymal transition in human lung vascular endothelial cells is Ca²⁺-dependent through store-operated Ca²⁺ entry via STIM1/Orai1 channels.

American Journal of Physiology-Lung Cellular and Molecular Physiology · May 7, 2025Peer-reviewedCell Biology