NeuroscienceAnnals of NeurologyPeer-reviewed
Resilience to Endoplasmic Reticulum Stress Mitigates Calcium-Dependent Membrane Hyperexcitability Underlying Late Disease Onset in SCA6
Haoran Huang, Taylor L. Charron, Min Fu…·Vikram G. Shakkottai
This study identifies ER stress and HSP90-dependent UPR as mechanisms underlying delayed onset of SCA6 motor dysfunction and Purkinje cell spiking abnormalities.
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