Author

Vigo Heissmeyer

Helmholtz MunichORCID 0000-0002-2263-8545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aida Muñoz Blázquez· 1 shared Almut DufneriD· 1 shared Ana-Marija Kulis-Mandic· 1 shared Anne‐Katrin PröbsteliD· 1 shared Antonia KolbiD· 1 shared Ari WaismaniD· 1 shared Arlinda NegraschusiD· 1 shared Bénédikt JacobsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperImmunology

Aida Muñoz Blázquez

Mutual co-authors in cluster

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3 papers

Recent·Most cited

USP8 Controls Proteostasis Pathways in B Cells and Multiple Myeloma

Almut Dufner, Fabien Théry, Gianni Monaco, Jelena Lazarevic, Oliver Gorka, Nina Chevalier, Marta Campos Alonso, Maximilian Frosch, Gerbrand J. van der Heden van Noort, Kira Allmeroth, Marco Prinz, Olaf Groß, Huib Ovaa, Paul P. Geurink, Wolfgang W A Schamel, , Klaus‐Peter Knobeloch

This study investigates the role of USP8 in B-cell development and multiple myeloma, showing its impact on proteostasis and identifying potential therapeutic strategies.

Leukemia · Aug 11, 2026Peer-reviewedMolecular Biology

Treg-derived IκBζ promotes their conversion into Th2-like effectors and drives type 2 inflammation via BATF

Tanja Kübelbeck, Ana-Marija Kulis-Mandic, Antonia Kolb, Emmanouil Stylianakis, Zeynep Ergün, Delia Mihaela Mihoc, Sara Salome Helbich, Kartikeya Singh, Matthias Klein, Niklas Beumer, Berenice Fischer, Stephan Hailfinger, Klaus Schulze‐Osthoff, Ari Waisman, Michael Delacher, , Daniela Kramer

This study identifies IκBζ as a key regulator of Treg cell plasticity, showing it drives their conversion into Th2-like effectors and promotes type 2 inflammation.

bioRxiv · Feb 24, 2026 · PreprintImmunology

Tmem127-mediated immune receptor degradation regulates T cell homeostasis through the common gamma chain

Marko Hasiuk, Arlinda Negraschus, Denis Seyres, Romina Marone, Gytis Jankevicius, Lena K. Siewert, Christoph Schultheiß, Aida Muñoz Blázquez, Mascha Binder, Anne‐Katrin Pröbstel, Sebastian Hiller, Vigo Heissmeyer, Lukas T. Jeker

The paper identifies Tmem127 as a regulator of T cell homeostasis by controlling IL-7 receptor surface expression and common gamma chain interactions.

bioRxiv · Jul 1, 2025 · PreprintImmunology