Author

Anne‐Katrin Pröbstel

University of BonnORCID 0000-0002-7748-1872Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Lena K. SiewertiD· 2 shared Aida Muñoz Blázquez· 1 shared Arlinda NegraschusiD· 1 shared Cecilia A. NoeckeriD· 1 shared Christine Olson· 1 shared Christoph SchultheißiD· 1 shared Denis SeyresiD· 1 shared Edwin Frank OrtegaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Lena K. SiewertORCID

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2 papers

Recent·Most cited

Female-enriched Eggerthella lenta drives neuroinflammation and IFN-γ via host receptor TLR2

Rachel R. Rock, Margaret Alexander, Cecilia A. Noecker, Kai R. Trepka, Vaibhav Upadhyay, Edwin Frank Ortega, Lorenzo Ramirez, Lena K. Siewert, Christine Olson, Taylor M. Halsey, Anne‐Katrin Pröbstel, Sergio E. Baranzini, Peter James Turnbaugh

The paper identifies a female-enriched gut bacterium, Eggerthella lenta, that drives neuroinflammation and IFN-γ via TLR2 in autoimmune disease models.

bioRxiv · Mar 23, 2026 · PreprintMicrobiology

Tmem127-mediated immune receptor degradation regulates T cell homeostasis through the common gamma chain

Marko Hasiuk, Arlinda Negraschus, Denis Seyres, Romina Marone, Gytis Jankevicius, Lena K. Siewert, Christoph Schultheiß, Aida Muñoz Blázquez, Mascha Binder, Anne‐Katrin Pröbstel, Sebastian Hiller, Vigo Heissmeyer, Lukas T. Jeker

The paper identifies Tmem127 as a regulator of T cell homeostasis by controlling IL-7 receptor surface expression and common gamma chain interactions.

bioRxiv · Jul 1, 2025 · PreprintImmunology